Experimental databases on inhibition of the bacterial mutagenicity of 4-nitroquinoline 1-oxide and cigarette smoke.

@article{Camoirano1994ExperimentalDO,
  title={Experimental databases on inhibition of the bacterial mutagenicity of 4-nitroquinoline 1-oxide and cigarette smoke.},
  author={Anna Camoirano and Roumen M Balansky and Carlo Bennicelli and Alberto Izzotti and Francesco D'Agostini and Silvio L De Flora},
  journal={Mutation research},
  year={1994},
  volume={317 2},
  pages={89-109}
}
Two antimutagenicity databases were prepared by applying a co-treatment procedure to the Salmonella reversion assay. Ninety compounds belonging to various chemical classes were quantitatively tested for antimutagenicity towards the direct-acting mutagen 4-nitroquinoline 1-oxide (4NQO) in strain TA100 of S. typhimurium and 63 of them were additionally tested for antimutagenicity towards unfractionated mainstream cigarette smoke (CS) in strain TA98, in the presence of S9 mix. Twelve compounds (13… CONTINUE READING