Experimental colitis models: Insights into the pathogenesis of inflammatory bowel disease and translational issues.

@article{Valatas2015ExperimentalCM,
  title={Experimental colitis models: Insights into the pathogenesis of inflammatory bowel disease and translational issues.},
  author={Vassilis Valatas and Giorgos Bamias and G Kolios},
  journal={European journal of pharmacology},
  year={2015},
  volume={759},
  pages={253-64}
}
Inflammatory bowel diseases, ulcerative colitis and Crohn׳s disease are characterized by chronic relapsing inflammation of the gastrointestinal tract of unknown etiology that seems to be the consequence of a genetically driven dysregulated immune response against various local and environmental triggers through a defective epithelial barrier. During the last decades, a large number of animal experimental models of intestinal inflammation have been generated and provided valuable insights into… CONTINUE READING
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