Experimental colitis alters myenteric nerve function at inflamed and noninflamed sites in the rat.

@article{Jacobson1995ExperimentalCA,
  title={Experimental colitis alters myenteric nerve function at inflamed and noninflamed sites in the rat.},
  author={Kevan Jacobson and Kevin H McHugh and Stephen M. Collins},
  journal={Gastroenterology},
  year={1995},
  volume={109 3},
  pages={718-22}
}
BACKGROUND & AIMS Studies in inflammatory bowel disease have shown extensive structural abnormalities in the enteric nervous system of inflamed and noninflamed gut; however, functional correlates are lacking. The aim of this study was to determine the effect of colitis on myenteric nerve function at inflamed and noninflamed sites in rat intestine. METHODS Tritiated noradrenaline release was measured from longitudinal muscle myenteric plexus preparations from the distal and transverse colon… CONTINUE READING

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