Experimental brush-evoked allodynia activates posterior parietal cortex

  title={Experimental brush-evoked allodynia activates posterior parietal cortex},
  author={Nanna Witting and Ron Kupers and Peter Svensson and Lars Arendt-Nielsen and Albert Gjedde and Troels Staehelin Jensen},
  pages={1817 - 1824}
Objective: To study the brain activation pattern of coexisting experimental ongoing pain and brush-evoked allodynia (pain evoked by innocuous brush) with the use of PET. Background: Neuropathic pain usually has two essential phenomena: ongoing pain and brush-evoked allodynia, which coexist and may influence each other. Capsaicin induces both ongoing pain and brush-evoked allodynia. Methods: Eight healthy right-handed volunteers participated in eight H215O PET scans with two blocks of four… 

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Comparisons of pain and vibrotactile stimulation revealed that both stimuli produced activation in similar regions of SI and SII, regions long thought to be involved in basic somatosensory processing, which reflects the complex nature of pain.