Experimental bladder carcinogenesis-rodent models.

  title={Experimental bladder carcinogenesis-rodent models.},
  author={Paula Alexandra Oliveira and Aura Antunes Colaço and P LuisFDelaCruz and Celia Mendes Carvalho Lopes},
  journal={Experimental oncology},
  volume={28 1},
Several rodent models of bladder cancer development have been established. The aim of this review article is to provide a critical assessment of different animal models available for the study of bladder carcinogenesis, its chemoprevention and therapy. All, except for transgenic and knockout animals, require 8-12 months experimental periods in order to generate a high yield of neoplasias. Spontaneous bladder tumor models are extremely rare. The significance of the results from animal… CONTINUE READING

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