Experimental autoimmune cystitis: a potential murine model for ulcerative interstitial cystitis.

@article{Bullock1992ExperimentalAC,
  title={Experimental autoimmune cystitis: a potential murine model for ulcerative interstitial cystitis.},
  author={Arnold D Bullock and Michael J. Becich and Carl Georg Klutke and Timothy L Ratliff},
  journal={The Journal of urology},
  year={1992},
  volume={148 6},
  pages={1951-6}
}
Interstitial cystitis is an inflammatory disease of unknown etiology. To facilitate the study of the pathophysiology of interstitial cystitis, an animal model that correlates with the clinical features of interstitial cystitis and expresses histologic features consistent with those observed in interstitial cystitis patients was developed. Various strains of mice were immunized with a syngeneic bladder homogenate to determine their susceptibility to the induction of autoimmune cystitis. Of 3… CONTINUE READING
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