Experimental aspects of intraabdominal abscess.

  title={Experimental aspects of intraabdominal abscess.},
  author={John G. Bartlett},
  journal={The American journal of medicine},
  volume={76 5A},
Two animal models were used to examine the bacteriologic aspects and antibiotic treatment of intraabdominal abscess. The first model was designed to simulate the septic complications of colonic perforation using an inoculum of stool implanted intraperitoneally in rats. The results showed that coliforms were responsible for early lethality, Bacteroides fragilis appeared to play a particularly important role in abscess formation, and optimal treatment required antimicrobial regimens directed… CONTINUE READING