Experimental antihyperglycemic effect of diterpenoids of llareta Azorella compacta (Umbelliferae) Phil in rats.

@article{Fuentes2005ExperimentalAE,
  title={Experimental antihyperglycemic effect of diterpenoids of llareta Azorella compacta (Umbelliferae) Phil in rats.},
  author={Nelson L Fuentes and Hern{\'a}n Sagua and Glauco Morales and Jorge B{\'o}rquez and Aurelio San Mart{\'i}n and Julia Soto and Luis Alberto Loyola},
  journal={Phytotherapy research : PTR},
  year={2005},
  volume={19 8},
  pages={713-6}
}
Aqueous or ethanol infusions of Azorella compacta (llareta) in common with many other plants have been used as antidiabetic in the popular medicine in the altiplanic region of Chile. In order to determine if the diterpenic compounds chemically elucidated and isolated from this plant are responsible for this effect, streptozotocin diabetic rats (507 +/- 67 mg/mL glucose) were injected with two injections of diterpenic compounds mulinolic acid, azorellanol, and mulin-11,13-dien-20-oic acid at 180… CONTINUE READING
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