Experimental annotation of the human pathogen Candida albicans coding and noncoding transcribed regions using high-resolution tiling arrays

@inproceedings{Sellam2010ExperimentalAO,
  title={Experimental annotation of the human pathogen Candida albicans coding and noncoding transcribed regions using high-resolution tiling arrays},
  author={Adnane Sellam and Herv{\'e} Hogues and Christopher D. Askew and Faiza Tebbji and Marco van het Hoog and Hugo Lavoie and Carol A. Kumamoto and Malcolm Whiteway and Andr{\'e} M. Nantel},
  booktitle={Genome Biology},
  year={2010}
}
Compared to other model organisms and despite the clinical relevance of the pathogenic yeast Candida albicans, no comprehensive analysis has been done to provide experimental support of its in silico-based genome annotation. We have undertaken a genome-wide experimental annotation to accurately uncover the transcriptional landscape of the pathogenic yeast C. albicans using strand-specific high-density tiling arrays. RNAs were purified from cells growing under conditions relevant to C. albicans… CONTINUE READING
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