Experimental and computational studies of the desensitization process in the bovine rhodopsin-arrestin complex.

Abstract

The deactivation of the bovine G-protein-coupled receptor, rhodopsin, is a two-step process consisting of the phosphorylation of specific serine and threonine residues in the cytoplasmic tail of rhodopsin by rhodopsin kinase. Subsequent binding of the regulatory protein arrestin follows this phosphorylation. Previous results find that at least three… (More)

Topics

  • Presentations referencing similar topics