Experimental and computational determination of the hydrodynamics of mini vessel dissolution testing systems.

Abstract

Mini vessel dissolution testing systems consist of a small-scale 100-mL vessel with a small paddle impeller, similar to the USP Apparatus 2, and are typically utilized when only small amounts of drug product are available during drug development. Despite their common industrial use, mini vessels have received little attention in the literature. Here… (More)
DOI: 10.1016/j.ijpharm.2016.06.036

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