Experimental and chemoinformatics evaluation of some physicochemical properties of excipients influencing release kinetics of the acidic drug ibuprofen.

@article{Gaikwad2015ExperimentalAC,
  title={Experimental and chemoinformatics evaluation of some physicochemical properties of excipients influencing release kinetics of the acidic drug ibuprofen.},
  author={Vinod L. Gaikwad and Manish Sudesh Bhatia and Indrajeet J. Singhvi},
  journal={Chemosphere},
  year={2015},
  volume={138},
  pages={494-502}
}
In the present study, ibuprofen, a nonsteroidal anti-inflammatory drug was used in the formulation of tablets using three polymers representing different categories (immediate, moderate and extended release). Prepared tablets were evaluated for different post-compression parameters including dissolution and transportability studies. In vitro dissolution… CONTINUE READING