Experimental allergic neuritis induced by a basic neuritogenic protein (P1L) of human peripheral nerve origin.

@article{Abramsky1977ExperimentalAN,
  title={Experimental allergic neuritis induced by a basic neuritogenic protein (P1L) of human peripheral nerve origin.},
  author={T O Abramsky and Dvora Teitelbaum and Ruth Arnon},
  journal={European journal of immunology},
  year={1977},
  volume={7 4},
  pages={213-7}
}
Experimental allergic neuritis (EAN) in the peripheral nervous system, without involvement of the central nervous system, was produced in laboratory animals by the injection of a basic neuritogenic protein, P1L, purified from human peripheral nerves. The animals manifested a positive skin test with P1L, and their lymphocytes were found to be transformed in vitro in the presence of this protein several days before the appearance of the clinical signs. Passive transfer of the disease was… CONTINUE READING