Experimental allergic encephalomyelitis in the monkey: humoral immunity and blood-brain barrier function

@article{Gallo2006ExperimentalAE,
  title={Experimental allergic encephalomyelitis in the monkey: humoral immunity and blood-brain barrier function},
  author={Patricia Gallo and Dragoslava Cupi{\'c} and Francesco Bracco and Lj. Kr{\vz}ali{\'c} and Prof. B. Tavolato and Leontino Battistin},
  journal={The Italian Journal of Neurological Sciences},
  year={2006},
  volume={10},
  pages={561-565}
}
Acute monophasic experimental autoimmune encephalomyelitis (AMEAE) was induced in 5 Macacus cynomolgus monkeys. Serum and cerebrospinal fluid (CSF) paired samples were colleced before and four weeks after immunization, time of complete development of AMEAE clinical picture. After immunization the CSF/serum albumin ratio and the IgG index were markedly increased. Agerose isoelectric focusing (AIEF) followed by immunofixation revealed faint IgG oligoclonal bands in both serum and CSF of all… CONTINUE READING

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