Experimental Traumatic Brain Injury Results in Long-Term Recovery of Functional Responsiveness in Sensory Cortex but Persisting Structural Changes and Sensorimotor, Cognitive, and Emotional Deficits.

@article{Johnstone2015ExperimentalTB,
  title={Experimental Traumatic Brain Injury Results in Long-Term Recovery of Functional Responsiveness in Sensory Cortex but Persisting Structural Changes and Sensorimotor, Cognitive, and Emotional Deficits.},
  author={Victoria Philippa Anne Johnstone and David K. Wright and Kendrew Wong and Terence J O'Brien and Ramesh Rajan and Sandy R Shultz},
  journal={Journal of neurotrauma},
  year={2015},
  volume={32 17},
  pages={
          1333-46
        }
}
Traumatic brain injury (TBI) is a leading cause of death worldwide. In recent studies, we have shown that experimental TBI caused an immediate (24-h post) suppression of neuronal processing, especially in supragranular cortical layers. We now examine the long-term effects of experimental TBI on the sensory cortex and how these changes may contribute to a range of TBI morbidities. Adult male Sprague-Dawley rats received either a moderate lateral fluid percussion injury (n=14) or a sham surgery… CONTINUE READING

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