Experimental Test of Connector Rotation during DNA Packaging into Bacteriophage ϕ29 Capsids


The bacteriophage phi29 generates large forces to compact its double-stranded DNA genome into a protein capsid by means of a portal motor complex. Several mechanical models for the generation of these high forces by the motor complex predict coupling of DNA translocation to rotation of the head-tail connector dodecamer. Putative connector rotation is… (More)


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