• Biology
  • Published 2007

Experimental Study on Tongxinluo Affecting the Expression of Caspase-3,P53 and HSP70 in Brain Tissue after Cerebral Ischemia of MCAO Model Rats

@inproceedings{Cong2007ExperimentalSO,
  title={Experimental Study on Tongxinluo Affecting the Expression of Caspase-3,P53 and HSP70 in Brain Tissue after Cerebral Ischemia of MCAO Model Rats},
  author={Wei Cong},
  year={2007}
}
Objective To approach the therapeutic mechanism of Tongxinluo(TXL) capsule in the conservative aspect of the cerebral ischemia.Methods SD rats were divided into five groups in random: sham operation group,MCAO(middle cerebral artery occlution) group,MK-801 group,TXL large dose group,TXL small dose group.After the preparation of MCAO,peritoneal injection of MK-801 0.5 mg/(kg·d) in MK-801 group,twice every day.TXL large dose group and TXL small dose group 1.0 g/(kg·d) and 0.5 g/(kg·d)respectively… CONTINUE READING