Corpus ID: 87241997

Experimental Studies on LCI-X7, a 7-amino Acid Peptide, Inhibited Invasiveness of Hepatocellular Carcinoma

@article{Ke2005ExperimentalSO,
  title={Experimental Studies on LCI-X7, a 7-amino Acid Peptide, Inhibited Invasiveness of Hepatocellular Carcinoma},
  author={Z. Ke},
  journal={Clinical Medical Journal of China},
  year={2005}
}
  • Z. Ke
  • Published 2005
  • Biology
  • Clinical Medical Journal of China
  • Objective: LCI-X7 is a 7-amino acid peptide, which was selected by in vivo phage display and specifically bound to several HCC cell lines and tumor vessels in hepatocellular carcinoma (HCC) in nude mice model. In this study, we tried to evaluate its in vitro and in vivo effects on HCC. Methods: The effects of LCI-X7 on proliferation, apoptosis, cell cycles, motility and invasiveness of HCCLM6 cell line were studied in vitro by MTT, flow cytometry, BrdU staining, Boyden chamber methods. Its… CONTINUE READING