Experience with split-course external beam irradiation +/- chemotherapy and integrated Ir-192 high-dose-rate brachytherapy in the treatment of primary carcinomas of the anal canal.

@article{Kapp2001ExperienceWS,
  title={Experience with split-course external beam irradiation +/- chemotherapy and integrated Ir-192 high-dose-rate brachytherapy in the treatment of primary carcinomas of the anal canal.},
  author={Karin Sigrid Kapp and Edith Geyer and Florian Gebhart and Astrid C Oechs and Antoine Berger and Jacques Hebenstreit and Herbert Stoeger},
  journal={International journal of radiation oncology, biology, physics},
  year={2001},
  volume={49 4},
  pages={997-1005}
}
PURPOSE The effect of the treatment of anal cancer by performing a high-dose-rate (HDR) brachytherapy boost during a short split between the external beam radiotherapy series (EBR) +/- chemotherapy was investigated. METHODS AND MATERIALS Thirty-nine patients with anal canal cancers, stages T1-T4 N0-2 M0, were treated with split-course EBR (50-50.4 Gy) and a Iridium 192 ((192)Ir-) HDR boost (6 Gy) performed during the 1-2-week split. Patients who failed to achieve a complete tumor response… CONTINUE READING

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