Experience with donors matched for minor blood group antigens in patients with sickle cell anemia who are receiving chronic transfusion therapy.

@article{Ambruso1987ExperienceWD,
  title={Experience with donors matched for minor blood group antigens in patients with sickle cell anemia who are receiving chronic transfusion therapy.},
  author={Daniel R. Ambruso and John H Githens and Ron Alcorn and D. F. Dixon and Laurence J R Brown and W M Vaughn and Taru Hays},
  journal={Transfusion},
  year={1987},
  volume={27 1},
  pages={94-8}
}
Clinically significant alloimmunization to red cell antigens occurred in 28 percent of transfused patients in a sickle cell clinic. Therefore, a prospective study was undertaken to determine whether matching donors carefully for 17 blood group antigens would diminish the risk of further alloimmunization in patients on a chronic transfusion program. Alloantibodies had developed previously in 8 of the 12 patients. After chronic transfusion with selected donors, four new antibodies developed in… CONTINUE READING

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