Experience with 5-fluoro-uracil and levamisole in the management of advanced rectal carcinoma.

@article{Ajao1996ExperienceW5,
  title={Experience with 5-fluoro-uracil and levamisole in the management of advanced rectal carcinoma.},
  author={Oluwole Gbolagunte Ajao and Olaitan Alice Soyannwo and Josephus K Ladipo and Linus Ikechukwu Okeke and Clement Adebamowo},
  journal={African journal of medicine and medical sciences},
  year={1996},
  volume={25 3},
  pages={239-41}
}
Eleven cases of bulky rectal carcinoma occupying the whole of the pelvis are presented. We refer to this advanced rectal carcinoma as "frozen" pelvis. Management of these cases includes performing a divided stoma colostomy, intravenous administration of 5-fluoro-uracil, intraperitoneal instillation of 5-fluoro-uracil when ascites is present, intra-rectal perfusion with 5-fluoro-uracil, administration of levamisole, and radiotherapy. We think this regimen improves, to some extent, the quality of… CONTINUE READING

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