Experience in the treatment of dedifferentiated chondrosarcoma.

  title={Experience in the treatment of dedifferentiated chondrosarcoma.},
  author={A. R. Mitchell and Karam F. Ayoub and David Chas Mangham and Robert J Grimer and Simon R. Carter and Roger M. Tillman},
  journal={The Journal of bone and joint surgery. British volume},
  volume={82 1},
Dedifferentiated chondrosarcoma is a rare, highly malignant variant of chondrosarcoma in which a high-grade spindle-cell sarcoma coexists with a lower-grade chondroid tumour. We have reviewed our experience with this neoplasm in 22 patients, all of whom were treated using modern oncological principles of planned resection and chemotherapy. Despite this the median survival was under nine months and only 18% were alive at five years. Those patients who received chemotherapy, and in whom wide… CONTINUE READING

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