Experience-Dependent Induction of Hippocampal ΔFosB Controls Learning.

@article{Eagle2015ExperienceDependentIO,
  title={Experience-Dependent Induction of Hippocampal ΔFosB Controls Learning.},
  author={Andrew L Eagle and Paula A. Gajewski and Miyoung Yang and Megan E Kechner and Basma S Al Masraf and Pamela J Kennedy and Hongbing Wang and Michelle S Mazei-Robison and Alfred J. Robison},
  journal={The Journal of neuroscience : the official journal of the Society for Neuroscience},
  year={2015},
  volume={35 40},
  pages={
          13773-83
        }
}
UNLABELLED The hippocampus (HPC) is known to play an important role in learning, a process dependent on synaptic plasticity; however, the molecular mechanisms underlying this are poorly understood. ΔFosB is a transcription factor that is induced throughout the brain by chronic exposure to drugs, stress, and variety of other stimuli and regulates synaptic plasticity and behavior in other brain regions, including the nucleus accumbens. We show here that ΔFosB is also induced in HPC CA1 and DG… CONTINUE READING
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