Expected versus observed survival in 3 large population studies with HMG-CoA reductase inhibitors.


OBJECTIVE HMG-CoA reductase inhibitors (statins) can lower low-density lipoprotein (LDL). We examined how they were used in three large recent population studies, shedding new light on the relationship between cholesterol levels and survival. METHODS Mortality observed in the placebo and treated groups of these primary and secondary prevention studies… (More)


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