Expectancy-related changes in firing of dopamine neurons depend on orbitofrontal cortex

  title={Expectancy-related changes in firing of dopamine neurons depend on orbitofrontal cortex},
  author={Yuji Takahashi and Matthew R Roesch and Robert C. Wilson and Kathy L Toreson and Patricio O’Donnell and Yael Niv and Geoffrey Schoenbaum},
  booktitle={Nature Neuroscience},
The orbitofrontal cortex has been hypothesized to carry information regarding the value of expected rewards. Such information is essential for associative learning, which relies on comparisons between expected and obtained reward for generating instructive error signals. These error signals are thought to be conveyed by dopamine neurons. To test whether orbitofrontal cortex contributes to these error signals, we recorded from dopamine neurons in orbitofrontal-lesioned rats performing a reward… CONTINUE READING
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