Expansion of human hematopoietic stem/progenitor cells on decellularized matrix scaffolds.

Abstract

Umbilical cord blood (UCB) is one of the richest sources for hematopoietic stem/progenitor cells (HSPCs), with more than 3000 transplantations performed each year for the treatment of leukemia and other bone marrow, immunological, and hereditary diseases. However, transplantation of single cord blood units is mostly restricted to children, due to the… (More)
DOI: 10.1002/9780470151808.sc01c15s28

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