Expansion of genes that encode MHC class I molecules in cyprinid fishes.

@article{Okamura1993ExpansionOG,
  title={Expansion of genes that encode MHC class I molecules in cyprinid fishes.},
  author={Kohji Okamura and Tohru Nakanishi and Yoshikazu Kurosawa and Katsuyuki Hashimoto},
  journal={Journal of immunology},
  year={1993},
  volume={151 1},
  pages={
          188-200
        }
}
We have analyzed the genomic genes and the mRNA that encode MHC class I molecules in cyprinid fishes, namely, the ginbuna crucian carp (Carassius auratus langsdorfii) and the carp (Cyprinus carpio). The presence of several distinct class I genes was revealed in the genome of cyprinid fishes, and distinct class I genes that are expressed in carp cells were identified. The sequences of the alpha 3 domain of these class I genes are relatively well conserved, whereas the sequences of the respective… CONTINUE READING

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