Expansion of an atypical NK cell subset in mouse models of systemic lupus erythematosus.


Chronic inflammatory conditions, such as in autoimmune disease, can disturb immune cell homeostasis and induce the expansion of normally rare cell populations. In our analysis of various murine models of lupus, we detect increased frequency of an uncommon subset identified as NK1.1(+)CD11c(+)CD122(+)MHC class II(+). These cells share characteristics with… (More)
DOI: 10.4049/jimmunol.1402673


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