Expansion of a clonal CD8+CD57+ large granular lymphocyte population after autologous stem cell transplant in multiple myeloma.

@article{Wolniak2013ExpansionOA,
  title={Expansion of a clonal CD8+CD57+ large granular lymphocyte population after autologous stem cell transplant in multiple myeloma.},
  author={Kristy L Wolniak and Charles L. Goolsby and Y-Hua Chen and Anjen Chenn and Seema B. Singhal and JayeshMehta and Lo Ann C Peterson},
  journal={American journal of clinical pathology},
  year={2013},
  volume={139 2},
  pages={231-41}
}
Clonal expansions of large granular lymphocytes (LGLs) have been identified in patients following stem cell transplants and may represent posttransplant LGL leukemias or reactive immune responses. To differentiate between these 2 possibilities, we assessed peripheral blood and bone marrow of patients with myeloma after autologous stem cell transplant. All patients examined shortly after autologous stem cell transplant had significant increases in the LGLs in the peripheral blood and bone marrow… CONTINUE READING
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