Expansion of CD8+ T cells with regulatory function after interaction with intestinal epithelial cells.


BACKGROUND & AIMS Regulatory T cells play a role in the control of immune responses in the intestinal mucosa and their absence may predispose to inflammatory bowel disease (IBD). We have previously shown that T cells activated by intestinal epithelial cells (IECs) are suppressive in function. Our goal was to characterize the phenotype and function of T… (More)


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