Expansion of CD19(hi)CD21(lo/neg) B cells in common variable immunodeficiency (CVID) patients with autoimmune cytopenia.

@article{Warnatz2002ExpansionOC,
  title={Expansion of CD19(hi)CD21(lo/neg) B cells in common variable immunodeficiency (CVID) patients with autoimmune cytopenia.},
  author={Klaus Warnatz and Claudia Wehr and Ruth Draeger and Sigune Schmidt and Hermann Eibel and Michael Schlesier and H U Peter},
  journal={Immunobiology},
  year={2002},
  volume={206 5},
  pages={502-13}
}
Common variable immunodeficiency (CVID) is characterized by a severe hypogammaglobulinemia. While the clinical picture is dominated by recurrent respiratory and gastrointestinal infections, a subgroup of up to 30% of the patients develops additional autoimmune phenomena, including thrombocytopenia and autoimmune hemolytic anemia. So far no classification allowed a prediction of the coincidence of immunodeficiency and autoimmunity. Here, we propose the size of the peripheral CD19(hi)CD2(lo/neg… CONTINUE READING