Expanding spectrum of human RYR2-related disease: new electrocardiographic, structural, and genetic features.

@article{Bhuiyan2007ExpandingSO,
  title={Expanding spectrum of human RYR2-related disease: new electrocardiographic, structural, and genetic features.},
  author={Zahurul A Bhuiyan and Maarten P. van den Berg and J Peter van Tintelen and Margreet T H E Bink-Boelkens and Ans C. P. Wiesfeld and Mari{\"e}lle Alders and Alex Vincent Postma and Irene Marijke Van Langen and Marcel M. A. M. Mannens and Arthur A. M. Wilde},
  journal={Circulation},
  year={2007},
  volume={116 14},
  pages={1569-76}
}
BACKGROUND Catecholaminergic polymorphic ventricular tachycardia is a disease characterized by ventricular arrhythmias elicited exclusively under adrenergic stress. Additional features include baseline bradycardia and, in some patients, right ventricular fatty displacement. The clinical spectrum is expanded by the 2 families described here. METHODS AND RESULTS Sixteen members from 2 separate families have been clinically evaluated and followed over the last 15 years. In addition to exercise… CONTINUE READING