Expanding role of pharmacogenomics in the management of cardiovascular disorders.

  title={Expanding role of pharmacogenomics in the management of cardiovascular disorders.},
  author={Vincent L M Yip and Munir Pirmohamed},
  journal={American journal of cardiovascular drugs : drugs, devices, and other interventions},
  volume={13 3},
Cardiovascular disease is a leading cause of death worldwide. Many pharmacologic therapies are available that aim to reduce the risk of cardiovascular disease but there is significant inter-individual variation in drug response, including both efficacy and toxicity. Pharmacogenetics aims to personalize medication choice and dosage to ensure that maximum clinical benefit is achieved whilst side effects are minimized. Over the past decade, our knowledge of pharmacogenetics in cardiovascular… CONTINUE READING
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