Expanding ester biosynthesis in Escherichia coli.

  title={Expanding ester biosynthesis in Escherichia coli.},
  author={Gabriel M. Rodriguez and Yohei Tashiro and Shota Atsumi},
  journal={Nature chemical biology},
  volume={10 4},
To expand the capabilities of whole-cell biocatalysis, we have engineered Escherichia coli to produce various esters. The alcohol O-acyltransferase (ATF) class of enzyme uses acyl-CoA units for ester formation. The release of free CoA upon esterification with an alcohol provides the free energy to facilitate ester formation. The diversity of CoA molecules found in nature in combination with various alcohol biosynthetic pathways allows for the biosynthesis of a multitude of esters. Small to… CONTINUE READING
Recent Discussions
This paper has been referenced on Twitter 15 times over the past 90 days. VIEW TWEETS

From This Paper

Figures, tables, results, connections, and topics extracted from this paper.
42 Extracted Citations
44 Extracted References
Similar Papers

Citing Papers

Publications influenced by this paper.
Showing 1-10 of 42 extracted citations

Referenced Papers

Publications referenced by this paper.
Showing 1-10 of 44 references

Lipase : a potential biocatalyst for the synthesis of valuable flavour and fragrance ester compounds

  • K. P. Dhake, D. D. Thakare, B. M. Bhanage
  • Flavour Fragrance J .
  • 2013

Metabolic engineering of Escherichia coli for limonene and perillyl alcohol production

  • J. Alonso-Gutierrez
  • Metab . Eng .
  • 2013

Similar Papers

Loading similar papers…