Expanded tissue targets for foamy virus replication with simian immunodeficiency virus-induced immunosuppression.

@article{Murray2006ExpandedTT,
  title={Expanded tissue targets for foamy virus replication with simian immunodeficiency virus-induced immunosuppression.},
  author={Shannon M Murray and Louis J. Picker and Michael K Axthelm and Maxine L. Linial},
  journal={Journal of virology},
  year={2006},
  volume={80 2},
  pages={663-70}
}
Foamy viruses (FV) are the oldest known genus of retroviruses and have persisted in nonhuman primates for over 60 million years. FV are efficiently transmitted, leading to a lifelong nonpathogenic infection. Transmission is thought to occur through saliva, but the detailed mechanism is unknown. Interestingly, this persistent infection contrasts with the rapid cytopathicity caused by FV in vitro, suggesting a host defense against FV. To better understand the tissue specificity of FV replication… CONTINUE READING

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