Expanded clinical and experimental use of SOX11 - using a monoclonal antibody

@inproceedings{Nordstrm2012ExpandedCA,
  title={Expanded clinical and experimental use of SOX11 - using a monoclonal antibody},
  author={Lena Nordstr{\"o}m and Ulrika Andreasson and Mats Jerkeman and Michael Dictor and Carl A. K. Borrebaeck and Sara Ek},
  booktitle={BMC Cancer},
  year={2012}
}
BackgroundThe transcription factor SOX11 is of diagnostic and prognostic importance in mantle cell lymphoma (MCL) and epithelial ovarian cancer (EOC), respectively. Thus, there is an unmet clinical and experimental need for SOX11-targeting assays with low background, high specificity and robust performance in multiple applications, including immunohistochemistry (IHC-P) and flow cytometry, which until now has been lacking.MethodsWe have developed SOX11-C1, a monoclonal mouse antibody targeting… CONTINUE READING

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