Expanded HOXA13 polyalanine tracts in a monotreme.

@article{Lehoczky2008ExpandedHP,
  title={Expanded HOXA13 polyalanine tracts in a monotreme.},
  author={Jessica A. Lehoczky and Jeffrey W. Innis},
  journal={Evolution & development},
  year={2008},
  volume={10 4},
  pages={
          433-8
        }
}
The N-terminal region of human HOXA13 has seven discrete polyalanine tracts. Our previous analysis of these tracts in multiple major vertebrate clades suggested that three are mammal-specific. We now report the N-terminal HOXA13 repetitive tract structures in the monotreme Tachyglossus aculeatus (echidna). Contrary to our expectations, echidna HOXA13 possesses a unique set of polyalanine tracts and an unprecedented polyglycine tract. The data support the conclusion that the emergence of… CONTINUE READING
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