Expandable var1 gene of yeast mitochondrial DNA: in-frame insertions can explain the strain-specific protein size polymorphisms.

@article{Hudspeth1984ExpandableVG,
  title={Expandable var1 gene of yeast mitochondrial DNA: in-frame insertions can explain the strain-specific protein size polymorphisms.},
  author={Michael E. S. Hudspeth and Robert D. Vincent and Philip S. Perlman and Deborah S. Shumard and L O Treisman and Lawrence I. Grossman},
  journal={Proceedings of the National Academy of Sciences of the United States of America},
  year={1984},
  volume={81 10},
  pages={3148-52}
}
The var1 locus of yeast mitochondrial DNA encodes a protein of the small mitochondrial ribosome subunit, denoted var1 protein. The size of var1 protein was previously shown to exhibit a strain-dependent polymorphism, determined by various combinations of at least three genetic elements. We report here that the var1 gene is itself polymorphic and that the six forms of this gene examined here differ by various combinations of three in-frame insertions into the coding region of the smallest allele… CONTINUE READING