Exosomes released from human induced pluripotent stem cells-derived MSCs facilitate cutaneous wound healing by promoting collagen synthesis and angiogenesis

@inproceedings{Zhang2015ExosomesRF,
  title={Exosomes released from human induced pluripotent stem cells-derived MSCs facilitate cutaneous wound healing by promoting collagen synthesis and angiogenesis},
  author={Jieyuan Zhang and Junjie Guan and Xin Niu and Guowen Hu and Shangchun Guo and Qing Feng Li and Zongping Xie and Changqing Zhang and Yang Wang},
  booktitle={Journal of Translational Medicine},
  year={2015}
}
Human induced pluripotent stem cell-derived mesenchymal stem cells (hiPSC-MSCs) have emerged as a promising alternative for stem cell transplantation therapy. Exosomes derived from mesenchymal stem cells (MSC-Exos) can play important roles in repairing injured tissues. However, to date, no reports have demonstrated the use of hiPSC-MSC-Exos in cutaneous wound healing, and little is known regarding their underlying mechanisms in tissue repair. hiPSC-MSC-Exos were injected subcutaneously around… CONTINUE READING
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