Exosomes in liver pathology.

  title={Exosomes in liver pathology.},
  author={Keisaku Sato and Fanyin Meng and Shannon S. Glaser and Gianfranco D Alpini},
  journal={Journal of hepatology},
  volume={65 1},
Exosomes are small (∼100nm) membrane-bound extracellular vesicles released by various types of cells into biological fluids. They contain proteins, mRNAs and miRNAs as cargo. Different cell types can take up exosomes by endocytosis and the cargo contained within them can be transferred horizontally to these recipient cells. Exosomal proteins and miRNAs can be functional and regulate physiological cell events modifying the microenvironment in target cells, a key event of liver pathology. Exosome… CONTINUE READING
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