Exosomes in human semen carry a distinctive repertoire of small non-coding RNAs with potential regulatory functions

@inproceedings{Vojtech2014ExosomesIH,
  title={Exosomes in human semen carry a distinctive repertoire of small non-coding RNAs with potential regulatory functions},
  author={Lucia Vojtech and Sangsoon Woo and Sean M Hughes and Claire Levy and Lamar Ballweber and Renan Sauteraud and Johanna Strobl and Katharine G. Westerberg and Raphael Gottardo and Muneesh Tewari and Florian Hladik},
  booktitle={Nucleic acids research},
  year={2014}
}
Semen contains relatively ill-defined regulatory components that likely aid fertilization, but which could also interfere with defense against infection. Each ejaculate contains trillions of exosomes, membrane-enclosed subcellular microvesicles, which have immunosuppressive effects on cells important in the genital mucosa. Exosomes in general are believed to mediate inter-cellular communication, possibly by transferring small RNA molecules. We found that seminal exosome (SE) preparations… CONTINUE READING
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