Exosomes from Dendritic Cells Loaded with Chaperone-Rich Cell Lysates Elicit a Potent T Cell Immune Response Against Intracranial Glioma in Mice

Abstract

Chaperone-rich cell lysates (CRCLs) may play an important role in the development of anti-tumor vaccines. Tumor-derived CRCLs have been reported to activate dendritic cells (DCs) to elicit potent anti-tumor activity. However, the role of DC-derived exosomes (DEXs) secreted from DCs loaded with CRCLs in the treatment of tumors has not been clearly determined… (More)
DOI: 10.1007/s12031-015-0506-9

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@article{Bu2015ExosomesFD, title={Exosomes from Dendritic Cells Loaded with Chaperone-Rich Cell Lysates Elicit a Potent T Cell Immune Response Against Intracranial Glioma in Mice}, author={Ning Bu and Haiqin Wu and Guilian Zhang and Shuqin Zhan and Ru Zhang and Hong Sun and Yun Du and Li Yao and Huqing Wang}, journal={Journal of Molecular Neuroscience}, year={2015}, volume={56}, pages={631-643} }