Exosomes: a common pathway for a specialized function.

  title={Exosomes: a common pathway for a specialized function.},
  author={Guillaume van Niel and Isabel Porto-Carreiro and Sabrina Simoes and Graça Raposo},
  journal={Journal of biochemistry},
  volume={140 1},
Exosomes are membrane vesicles that are released by cells upon fusion of multivesicular bodies with the plasma membrane. Their molecular composition reflects their origin in endosomes as intraluminal vesicles. In addition to a common set of membrane and cytosolic molecules, exosomes harbor unique subsets of proteins linked to cell type-associated functions. Exosome secretion participates in the eradication of obsolete proteins but several findings, essentially in the immune system, indicate… CONTINUE READING
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