Exosome lipidomics unravels lipid sorting at the level of multivesicular bodies.

  title={Exosome lipidomics unravels lipid sorting at the level of multivesicular bodies.},
  author={Caroline Subra and Karine Laulagnier and Bertrand Perret and Michel Record},
  volume={89 2},
Exosomes are part of the family of "bioactive vesicles" and appear to be involved in distal communications between cells. They vehiculate bioactive lipids and lipolytic enzymes and their biogenesis require specific lipids and a membrane reorganisation. Their biogenesis pathway could be a way to secrete enzymes involved in lipid signalling and to generate "particulate agonists". However, this pathway seems also to be used by pathogens such as HIV. This review will consider several aspects of… CONTINUE READING

From This Paper

Figures, tables, and topics from this paper.


Publications citing this paper.
Showing 1-10 of 137 extracted citations


Publications referenced by this paper.
Showing 1-10 of 57 references


  • T. Kobayashi, E. Stang, K. S. Fang
  • de Moerloose, R.G. Parton, J. Gruenberg, A lipid…
  • 1998
Highly Influential
4 Excerpts


  • A. Schweizer, H. Clausen
  • van Meer, H.P. Hauri, Localization of O-glycan…
  • 1994
Highly Influential
4 Excerpts


  • W. Mobius
  • van Donselaar, Y. Ohno-Iwashita, Y. Shimada, H.F…
  • 2003
Highly Influential
3 Excerpts

Similar Papers

Loading similar papers…