Exosome lipidomics unravels lipid sorting at the level of multivesicular bodies.

@article{Subra2007ExosomeLU,
  title={Exosome lipidomics unravels lipid sorting at the level of multivesicular bodies.},
  author={Caroline Subra and Karine Laulagnier and Bertrand Perret and Michel Record},
  journal={Biochimie},
  year={2007},
  volume={89 2},
  pages={205-12}
}
Exosomes are part of the family of "bioactive vesicles" and appear to be involved in distal communications between cells. They vehiculate bioactive lipids and lipolytic enzymes and their biogenesis require specific lipids and a membrane reorganisation. Their biogenesis pathway could be a way to secrete enzymes involved in lipid signalling and to generate "particulate agonists". However, this pathway seems also to be used by pathogens such as HIV. This review will consider several aspects of… CONTINUE READING

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