Exosomal proteins as prognostic biomarkers in non-small cell lung cancer.

@article{SandfeldPaulsena2016ExosomalPA,
  title={Exosomal proteins as prognostic biomarkers in non-small cell lung cancer.},
  author={B. Sandfeld-Paulsena and N. Aggerholm-Pedersenb and R. B{\ae}kc and K. R. Jakobsena and Peter Meldgaardb and B. H. Folkersene and T. R. Rasmussene and K. Varmingc and M. M. J{\o}rgensenc and Boe Sandahl Sorensena},
  journal={Molecular oncology},
  year={2016},
  volume={10 10},
  pages={1595-1602}
}
BACKGROUND Use of exosomes as biomarkers in non-small cell lung cancer (NSCLC) is an intriguing approach in the liquid-biopsy era. Exosomes are nano-sized vesicles with membrane-bound proteins that reflect their originating cell. Prognostic biomarkers are needed to improve patient selection for optimal treatment. We here evaluate exosomes by protein phenotyping as a prognostic biomarker in NSCLC. METHODS Exosomes from plasma of 276 NSCLC patients were phenotyped using the Extracellular… CONTINUE READING

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