Exosomal lncRNA-p21 levels may help to distinguish prostate cancer from benign disease

@inproceedings{In2015ExosomalLL,
  title={Exosomal lncRNA-p21 levels may help to distinguish prostate cancer from benign disease},
  author={Mustafa Işın and Ege Uysaler and Emre {\"O}zg{\"u}r and Hikmet K{\"o}seoğlu and {\"O}ner Şanlı and {\"O}mer Barış Y{\"u}cel and Uğur Gezer and Nejat Dalay},
  booktitle={Front. Genet.},
  year={2015}
}
Exosomes are membranous vesicles containing various biomolecules including lncRNAs which are involved in cellular communication and are secreted from many cells including cancer cells. In our study, investigated the exosomal GAS5 and lincRNA-p21 lncRNA levels in urine samples from 30 patients with prostate cancer (PCa) and 49 patients with benign prostatic hyperplasia. Quantification of lncRNA molecules was performed by real-time PCR. We observed a significant difference in the exosomal lincRNA… CONTINUE READING
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