Exosomal Proteins as Diagnostic Biomarkers in Lung Cancer.

@article{SandfeldPaulsen2016ExosomalPA,
  title={Exosomal Proteins as Diagnostic Biomarkers in Lung Cancer.},
  author={Birgitte Sandfeld-Paulsen and Kristine Raaby Jakobsen and Rikke B{\ae}k and Birgitte Folkersen and Torben R Rasmussen and Peter Meldgaard and Kim Varming and Malene M J\orgensen and Boe Sandahl Sorensen},
  journal={Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer},
  year={2016},
  volume={11 10},
  pages={1701-10}
}
INTRODUCTION Exosomes have been suggested as promising biomarkers in NSCLC because they contain proteins from their originating cells and are readily available in plasma. In this study, we explored the potential of exosome protein profiling in diagnosing lung cancers of all stages and various histological subtypes in patients. METHODS Plasma was isolated from 581 patients (431 with lung cancer and 150 controls). The extracellular vesicle array was used to phenotype exosomes. The extracellular… CONTINUE READING
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