Exopolysaccharide-associated protein sorting in environmental organisms: the PEP-CTERM/EpsH system. Application of a novel phylogenetic profiling heuristic

@article{Haft2006ExopolysaccharideassociatedPS,
  title={Exopolysaccharide-associated protein sorting in environmental organisms: the PEP-CTERM/EpsH system. Application of a novel phylogenetic profiling heuristic},
  author={Daniel H. Haft and Ian T. Paulsen and Naomi L. Ward and Jeremy D. Selengut},
  journal={BMC Biology},
  year={2006},
  volume={4},
  pages={29 - 29}
}
Protein translocation to the proper cellular destination may be guided by various classes of sorting signals recognizable in the primary sequence. Detection in some genomes, but not others, may reveal sorting system components by comparison of the phylogenetic profile of the class of sorting signal to that of various protein families. We describe a short C-terminal homology domain, sporadically distributed in bacteria, with several key characteristics of protein sorting signals. The domain… CONTINUE READING
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