Exogenous sialic acid transport contributes to group B streptococcus infection of mucosal surfaces.

@article{Pezzicoli2012ExogenousSA,
  title={Exogenous sialic acid transport contributes to group B streptococcus infection of mucosal surfaces.},
  author={Alfredo Pezzicoli and Paolo Ruggiero and Fulvia Amerighi and John L. Telford and Marco Soriani},
  journal={The Journal of infectious diseases},
  year={2012},
  volume={206 6},
  pages={
          924-31
        }
}
By sequence analysis of available group B streptococcus (GBS) genomes, we discovered a conserved putative operon involved in the catabolism of sialic acid, containing a tripartite transporter formed by two integral membrane components and a sugar-binding unit, named SAL0039. Expression analysis in the presence of different substrates revealed that SAL0039 was specifically upregulated by the presence of sialic acid and downregulated when bacteria were grown in human blood or in the presence of a… CONTINUE READING

Citations

Publications citing this paper.
SHOWING 1-10 OF 10 CITATIONS

References

Publications referenced by this paper.
SHOWING 1-10 OF 31 REFERENCES

Complications of viral in fl uen

  • MB Rothberg, SD Haessler, RB Brown
  • Am J Med
  • 2008

Similar Papers

Loading similar papers…