Exogenous glutathione completes the defense against oxidative stress in Haemophilus influenzae.

@article{Vergauwen2003ExogenousGC,
  title={Exogenous glutathione completes the defense against oxidative stress in Haemophilus influenzae.},
  author={Bjorn Vergauwen and Frederik Pauwels and Mario Vaneechoutte and Jozef J. Van Beeumen},
  journal={Journal of bacteriology},
  year={2003},
  volume={185 5},
  pages={1572-81}
}
Since they are equipped with several strategies by which they evade the antimicrobial defense of host macrophages, it is surprising that members of the genus Haemophilus appear to be deficient in common antioxidant systems that are well established to protect prokaryotes against oxidative stress. Among others, no genetic evidence for glutathione (gamma-Glu-Cys-Gly) (GSH) biosynthesis or for alkyl hydroperoxide reduction (e.g., the Ahp system characteristic or enteric bacteria) is apparent from… CONTINUE READING

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